A Modified Potency Test Strategy for IV Admixtures Prepared by Robotic Systems

Authors

Fang Zhao, St. John Fisher UniversityFollow
Vivek S. Dave, St. John Fisher UniversityFollow
Susan E. Hughes, University of RochesterFollow

Document Type

Poster Presentation

Publication Date

7-13-2015

Keywords

fsc2015

Abstract

Introduction:

Robotic systems are increasingly used for compounding sterile IV admixtures (1-5). In addition to routine gravimetric checks, initial and periodic drug potency analysis by high-performance liquid chromatography (HPLC) is desired to verify the system accuracy. However, the conventional HPLC test procedures often result in unexpected failures (1-2).

This study was initiated to develop a modified HPLC test strategy to eliminate the common source of variability and focus the effort on the accuracy of robotic system.

Comments

Presented at the American Association of Colleges of Pharmacy (AACP) Annual Meeting in National Harbor, Maryland, July 13, 2015.

Publication Information

Zhao, Fang; Dave, Vivek S.; and Hughes, Susan E., "A Modified Potency Test Strategy for IV Admixtures Prepared by Robotic Systems" (2015). Pharmacy Faculty/Staff Publications. Paper 63.
https://fisherpub.sjf.edu/pharmacy_facpub/63

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