Robotic systems are increasingly used for compounding sterile IV admixtures (1-5). In addition to routine gravimetric checks, initial and periodic drug potency analysis by high-performance liquid chromatography (HPLC) is desired to verify the system accuracy. However, the conventional HPLC test procedures often result in unexpected failures (1-2).
This study was initiated to develop a modified HPLC test strategy to eliminate the common source of variability and focus the effort on the accuracy of robotic system.
Zhao, Fang; Dave, Vivek S.; and Hughes, Susan E., "A Modified Potency Test Strategy for IV Admixtures Prepared by Robotic Systems" (2015). Pharmacy Faculty/Staff Publications. Paper 63.
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