In lieu of an abstract, here is the chapter's first paragraph:
Digitalis is the oldest cardiovascular compound still in use today.1 More than 200 years ago, Sir William Withering observed that foxglove flower derivative (digitalis purpura) could be used for “cardiac dropsy.”2 Since that time, the positive hemodynamic, neurohormonal, and electrophysiologic effects of digoxin have been well explored.1
Noviasky, John; Darko, William; Akajabor, Darowan; Makaron, Arkadiy; Miller, Christopher; Pierce, Deirdre P.; Seabury, Robert; and Whalen, Karen (2015). "Digoxin." Casebook in Clinical Pharmacokinetics and Drug Dosing , 65-78.
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