Aim: To retrospectively evaluate the use of proton pump inhibitor infusions.
Methods: A retrospective chart review was conducted of all patients who received an 80 mg bolus of esomeprazole follow by an infusion at 8 mg/hr. An analysis was performed to determine if a Blatchford Score of > 5 was a predictor of upper gastrointestinal ulcers.
Results: 300 patients received high dose esomeprazole over a 15 month period. 32% had an ulcer identified on endoscopy. Gastritis and esophagitis were the second most common diagnosis accounting for 16% of patients. A Blatchford Score of >5 as a predictor of upper gastrointestinal ulcers had a sensitivity of 86.5% with a specificity of 32%.
Conclusion: Utilizing the Blatchford Score to predict patients that have an upper gastrointestinal ulcer does not appear to be effective in clinical practice.
Fellows, Shawn E. and Rosini, Jamie M. (2017). "Practical use of blactchford score." MOJ Bioequivalence & Bioavailability 3.3, 65-68.
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