IL-1 Generated Subsequent to Radiation-induced Tissue Injury Contributes to the Pathogenesis of Radiodermatitis
Radiodermatitis is a condition in which the skin becomes inflamed and the epidermis can break down following radiation injury. In this study we developed a murine model of radiodermatitis where the skin is selectively injured by high-energy electron radiation. Using this model we investigated the interleukin-1 (IL-1) pathway in the development of radiodermatitis.
Janko, Matthew; Ontiveros, Fernando; Fitzgerald, T. J.; Deng, A.; DeCicco, M.; and Rock, Kenneth L. (2012). "IL-1 Generated Subsequent to Radiation-induced Tissue Injury Contributes to the Pathogenesis of Radiodermatitis." International Journal of Radiation Oncology Biology Physics 84.3, Supplement, S679-S679.
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